HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Cyclopropylthiazol-4-yl)methanamine → 6-(4-Chloro-phenyl)-5-cyclopropylmethoxy-pyridine-2-carboxylic acid (2-cyclopropyl-thiazol-4-ylmethyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Cyclopropylthiazol-4-yl)methanamine | HCID 45792629 | — |
| Reactant | 6-(4-Chloro-phenyl)-5-cyclopropylmethoxy-pyridine-2-carboxylic acid | HCID 66678605 | — |
| Product | 6-(4-Chloro-phenyl)-5-cyclopropylmethoxy-pyridine-2-carboxylic acid (2-cyclopropyl-thiazol-4-ylmethyl)-amide | HCID 56928906 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 41 using 6-(4-Chloro-phenyl)-5-cyclopropylmethoxy-pyridine-2-carboxylic acid (example AW) and 2-cyclopropyl-4-thiazolemethanamine (CAN. 1083299-53-9) as starting materials, LC-MS (UV peak area/ESI) 95.5%, 440.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09090599B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-82664b6d532641b3816e959c70425b69 |
| Source note | uspto-grants-2015_07 |