HuagongsheHuagongshe Chemistry Print Report · For research reference only
[3-(Trifluoromethyl)-1,2-oxazol-5-yl]methanamine → 5-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridazine-3-carboxylic acid (3-trifluoromethyl-isoxazol-5-ylmethyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [3-(Trifluoromethyl)-1,2-oxazol-5-yl]methanamine | HCID 54405670 | — |
| Reactant | HCID 66678582 | HCID 66678582 | — |
| Product | 5-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridazine-3-carboxylic acid (3-trifluoromethyl-isoxazol-5-ylmethyl)-amide | HCID 56929003 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 5-(4-chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridazine-3-carboxylic acid (example M) and 3-trifluoromethyl-isoxazol-5-methanamine (example BA) as starting materials; MS: 480.0 (M)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09090599B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-1cf330a2389746768c5bd16cd18061d9 |
| Source note | uspto-grants-2015_07 |