HuagongsheHuagongshe Chemistry Print Report · For research reference only
[3-(Trifluoromethyl)-1,2-oxazol-5-yl]methanamine → 4-(4-Chloro-phenyl)-5-(2,2,2-trifluoro-ethoxy)-pyrimidine-2-carboxylic acid (3-trifluoromethyl-isoxazol-5-ylmethyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [3-(Trifluoromethyl)-1,2-oxazol-5-yl]methanamine | HCID 54405670 | — |
| Reactant | HCID 66686794 | HCID 66686794 | — |
| Product | 4-(4-Chloro-phenyl)-5-(2,2,2-trifluoro-ethoxy)-pyrimidine-2-carboxylic acid (3-trifluoromethyl-isoxazol-5-ylmethyl)-amide | HCID 56929004 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 4-(4-chloro-phenyl)-5-(2,2,2-trifluoro-ethoxy)-pyrimidine-2-carboxylic acid (example AA) and 3-trifluoromethyl-isoxazol-5-methanamine (example BA) as starting materials; MS: 481.0 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09090599B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-03fc9105a631416383f09a34f88ed7aa |
| Source note | uspto-grants-2015_07 |