HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 66678582, compound → 5-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridazine-3-carboxylic acid (5-trifluoromethyl-isoxazol-3-ylmethyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 66678582 | HCID 66678582 | — |
| Reactant | [5-(Trifluoromethyl)-1,2-oxazol-3-yl]methanamine | HCID 66678829 | — |
| Product | 5-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridazine-3-carboxylic acid (5-trifluoromethyl-isoxazol-3-ylmethyl)-amide | HCID 56929099 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 41 using 5-(4-chlorophenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridazine-3-carboxylic acid (example M) and 5-trifluoromethyl-isoxazol-3-methanamine (example BF) as starting materials; LC-MS (UV peak area/ESI), 94.3%, 481.3 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09090599B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-c0d8b58184fd4bb8ba7bae9c0986f7ce |
| Source note | uspto-grants-2015_07 |