HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-(Trifluoromethyl)-1,2,4-oxadiazol-5-YL)methanamine → 4-(3,4-dimethylphenyl)-5-(2,2,2-trifluoroethoxy)-N-((3-(trifluoromethyl)-1,2,4-oxadiazol-5-yl)methyl)picolinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-(Trifluoromethyl)-1,2,4-oxadiazol-5-YL)methanamine | HCID 55263061 | — |
| Reactant | 4-(3,4-Dimethylphenyl)-5-(2,2,2-trifluoroethoxy)picolinic acid | HCID 66678795 | — |
| Product | 4-(3,4-dimethylphenyl)-5-(2,2,2-trifluoroethoxy)-N-((3-(trifluoromethyl)-1,2,4-oxadiazol-5-yl)methyl)picolinamide | HCID 56929277 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1 using 4-(3,4-dimethylphenyl)-5-(2,2,2-trifluoroethoxy)picolinic acid (example BO) and 3-trifluoromethyl-[1,2,4]oxadiazol-5-methanamine (example AK) as starting materials; LC-MS (UV peak area/ESI) 100%, 475.1211 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09090599B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-a9c94eb058434429ae2c8cb4ef9efe31 |
| Source note | uspto-grants-2015_07 |