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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1528503Generated: November 3, 2026

2-Pyridinemethanamine → 5-(4-chlorophenyl)-6-cyclobutoxy-N-(pyridin-2-ylmethyl)nicotinamide

https://huagongshe.com/reaction/1528503

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-PyridinemethanamineHCID 19509—
Reactant5-(4-Chlorophenyl)-6-cyclobutoxy-nicotinic acidHCID 66678618—
Product5-(4-chlorophenyl)-6-cyclobutoxy-N-(pyridin-2-ylmethyl)nicotinamideHCID 56929564—

Reaction Steps

The title compound was synthesized in analogy to Example 1 using 5-(4-chlorophenyl)-6-cyclobutoxy-nicotinic acid (example CA) and 2-pyridinemethanamine (CAN 3731-51-9) as starting materials; LC-MS (UV peak area/ESI) 99.0%, 394.1 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09090599B2
Source datasetuspto-grants-2015_07
ORD IDord-430357dda09c4fe89726f6737ea9cdda
Source noteuspto-grants-2015_07