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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1528564Generated: November 2, 2026

1,2-Dibromoethane → 1-(5-Bromopyridin-2-yl)cyclopropane-1-carbonitrile

https://huagongshe.com/reaction/1528564

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DibromoethaneHCID 7839—
Reactant(5-Bromopyridin-2-yl)acetonitrileHCID 29927881—
Product1-(5-Bromopyridin-2-yl)cyclopropane-1-carbonitrileHCID 5340299088%

Reaction Steps

Alternatively, the title compound was prepared from (5-bromo-pyridin-2-yl)-acetonitrile and 1,2-dibromoethane following a procedure analogous to that described in Step 3 for Intermediate 4. Yield: 88% of theory.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09090605B2
Source datasetuspto-grants-2015_07
ORD IDord-5c882792113d4bbd9aff6683d8b7fac0
Source noteuspto-grants-2015_07