5-Bromo-2-hydroxypyridine → HCID 67997449, compound

HRID 1528610Notes

Reaction equation

[Br:1][C:2]1[CH:3]=[CH:4][C:5](=[O:8])[NH:6][CH:7]=1.I[CH:10]1[CH2:13][O:12][CH2:11]1>>[Br:1][C:2]1[CH:3]=[CH:4][C:5](=[O:8])[N:6]([CH:10]2[CH2:13][O:12][CH2:11]2)[CH:7]=1

Participants

Reactant 2

HCID 5995285-Bromo-2-hydroxypyridine

HCID 133566863-Iodooxetane

Product 1

HCID 67997449HCID 67997449, compound

Procedure

The title compound was prepared from 5-bromopyridin-2(1H)-one and 3-iodooxetane following a procedure analogous to that described for Intermediate 22.

Sources & evidence

ORD record: ord-294f92da48d841dca66cd88a48732bd2
Source dataset: uspto-grants-2015_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09090605B2

Reaction notes

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