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HRID1528627

反应详情

EQUATION

反应方程式

HRID 1528627 的结构方程式

REACTANTS

反应物

2
结构：O=c1cc(Br)ccn1[C@@H]1CCOC1
HCID58564190

未命名化合物

结构：C[C@@H](c1ccc(B2OC(C)(C)C(C)(C)O2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O
HCID59532385

(S)-6-(2-hydroxy-2-methylpropyl)-6-phenyl-3-((S)-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethyl)-1,3-oxazinan-2-one

C28H38BNO5

PRODUCTS

生成物

1
结构：C[C@@H](c1ccc(-c2ccn([C@@H]3CCOC3)c(=O)c2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O
HCID54771080

未命名化合物

收率 65%

PROCEDURE

实验过程

The title compound was prepared from (S)-6-(2-hydroxy-2-methylpropyl)-6-phenyl-3-{(S)-1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-ethyl}-1,3-oxazinan-2-one and 4-bromo-1-[(R)-tetrahydro-furan-3-yl]-1H-pyridin-2-one following a procedure analogous to that described in Example 1. Yield: 65% of theory; LC (method 3): tR=2.95 min; Mass spectrum (ESI+): m/z=517 [M+H]+.