(2-Chlorophenyl)methanesulfonyl chloride → HCID 66578260, compound

HRID 1528711Notes

Reaction equation

HRID 1528711 reaction equation
[CH2:1]([O:3][C:4]([C:6]1([C:9]2[CH:14]=[CH:13][C:12]([C:15]3[CH:20]=[CH:19][C:18]([C:21]4[O:25][N:24]=[C:23]([CH3:26])[C:22]=4[NH2:27])=[CH:17][CH:16]=3)=[CH:11][CH:10]=2)[CH2:8][CH2:7]1)=[O:5])[CH3:2].[Cl:28][C:29]1[CH:39]=[CH:38][CH:37]=[CH:36][C:30]=1[CH2:31][S:32](Cl)(=[O:34])=[O:33]>>[CH2:1]([O:3][C:4]([C:6]1([C:9]2[CH:10]=[CH:11][C:12]([C:15]3[CH:20]=[CH:19][C:18]([C:21]4[O:25][N:24]=[C:23]([CH3:26])[C:22]=4[NH:27][S:32]([CH2:31][C:30]4[CH:36]=[CH:37][CH:38]=[CH:39][C:29]=4[Cl:28])(=[O:33])=[O:34])=[CH:17][CH:16]=3)=[CH:13][CH:14]=2)[CH2:8][CH2:7]1)=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 2757801(2-Chlorophenyl)methanesulfonyl chlorideHCID 665771951-[4'-(4-Amino-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester

Product 1

HCID 66578260HCID 66578260, compound

Procedure

Prepared according to the procedure described in Example 3, Step 7, using 1-[4′-(4-amino-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester and 2-chlorobenzylsulfonyl chloride.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-6f8243bf0ede4ce68c81ee589f12f6ad
Source dataset
uspto-grants-2015_07
Patent number
US09090573B2

Reaction notes

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