HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenepropanal → HCID 66577253, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenepropanal | HCID 7707 | — |
| Reactant | Sodium cyanoborohydride | HCID 5003444 | — |
| Reactant | 5-(4-Bromophenyl)-3-methylisoxazol-4-amine | HCID 58218537 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 66577253 | HCID 66577253 | — |
Reaction Steps
5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-ylamine (0.300 g, 1.19 mmol), hydrocinnamaldehyde (0.192 g, 1.43 mmol), and sodium cyanoborohydride (0.188 g, 2.99 mmol) were combined in CH2Cl2 and stirred overnight at room temperature. After aqueous workup, the crude material was purified by silica gel chromatography to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09090573B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-50ca147bfbbc4bf9800bb0c0877adecb |
| Source note | uspto-grants-2015_07 |