HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → 1-[4'-(4-{[Acetyl-(2-phenyl-propyl)-amino]-methyl}-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | 1-(4'-{3-Methyl-4-[(2-phenyl-propylamino)-methyl]-isoxazol-5-yl}-biphenyl-4-yl)-cyclopropanecarboxylic acid ethyl ester | HCID 66577275 | — |
| Product | 1-[4'-(4-{[Acetyl-(2-phenyl-propyl)-amino]-methyl}-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester | HCID 66578202 | — |
Reaction Steps
Prepared according to the procedure described in Example 3, Step 7, using 1-(4′-{3-methyl-4-[(2-phenyl-propylamino)-methyl]-isoxazol-5-yl}-biphenyl-4-yl)-cyclopropanecarboxylic acid ethyl ester and acetyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09090573B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-142d13702d7748ff853b993029f91629 |
| Source note | uspto-grants-2015_07 |