2-Phenoxypropanoyl chloride → HCID 66578192, compound

HRID 1528806Notes

Reaction equation

HRID 1528806 reaction equation
[CH2:1]([O:3][C:4]([C:6]1([C:9]2[CH:14]=[CH:13][C:12]([C:15]3[CH:20]=[CH:19][C:18]([C:21]4[O:25][N:24]=[C:23]([CH3:26])[C:22]=4[CH2:27][NH:28][CH3:29])=[CH:17][CH:16]=3)=[CH:11][CH:10]=2)[CH2:8][CH2:7]1)=[O:5])[CH3:2].[O:30]([CH:37]([CH3:41])[C:38](Cl)=[O:39])[C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1>>[CH2:1]([O:3][C:4]([C:6]1([C:9]2[CH:10]=[CH:11][C:12]([C:15]3[CH:20]=[CH:19][C:18]([C:21]4[O:25][N:24]=[C:23]([CH3:26])[C:22]=4[CH2:27][N:28]([CH3:29])[C:38](=[O:39])[CH:37]([O:30][C:31]4[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=4)[CH3:41])=[CH:17][CH:16]=3)=[CH:13][CH:14]=2)[CH2:8][CH2:7]1)=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 954362-Phenoxypropanoyl chlorideHCID 66578153HCID 66578153, compound

Product 1

HCID 66578192HCID 66578192, compound

Procedure

Prepared according to the procedure described in Example 3, Step 7, using 1-[4′-(3-methyl-4-methylaminomethyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester and 2-phenoxy-propionyl chloride.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-fe27fa8110f548e4b25782e2561f9b89
Source dataset
uspto-grants-2015_07
Patent number
US09090573B2

Reaction notes

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