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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1528807Generated: November 4, 2026

Cyclopropanecarbonyl chloride → 1-[4'-(4-{[Cyclopropanecarbonyl-(2-phenyl-propyl)-amino]-methyl}-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester

https://huagongshe.com/reaction/1528807

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropanecarbonyl chlorideHCID 77637—
Reactant1-(4'-{3-Methyl-4-[(2-phenyl-propylamino)-methyl]-isoxazol-5-yl}-biphenyl-4-yl)-cyclopropanecarboxylic acid ethyl esterHCID 66577275—
Product1-[4'-(4-{[Cyclopropanecarbonyl-(2-phenyl-propyl)-amino]-methyl}-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl esterHCID 66578169—

Reaction Steps

Prepared according to the procedure described in Example 3, Step 7, using 1-(4′-{3-Methyl-4-[(2-phenyl-propylamino)-methyl]-isoxazol-5-yl}-biphenyl-4-yl)-cyclopropanecarboxylic acid ethyl ester and cyclopropanecarbonyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09090573B2
Source datasetuspto-grants-2015_07
ORD IDord-8ca3fd2f9dfe4ddb933fe728e5a9543e
Source noteuspto-grants-2015_07