Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1528812Generated: November 3, 2026

(1-Bromoethyl)benzene → 1-(4'-{3-Methyl-4-[2-(1-phenyl-ethoxy)-ethyl]-isoxazol-5-yl}-biphenyl-4-yl)-cyclopropanecarboxylic acid

https://huagongshe.com/reaction/1528812

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1-Bromoethyl)benzeneHCID 11454—
Reactant1-{4'-[4-(2-Hydroxy-ethyl)-3-methyl-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl esterHCID 66577266—
Product1-(4'-{3-Methyl-4-[2-(1-phenyl-ethoxy)-ethyl]-isoxazol-5-yl}-biphenyl-4-yl)-cyclopropanecarboxylic acidHCID 51352397—

Reaction Steps

Prepared according to the procedure described in Example 34, Step 4, using 1-{4′-[4-(2-hydroxy-ethyl)-3-methyl-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl ester and (1-bromoethyl)benzene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09090573B2
Source datasetuspto-grants-2015_07
ORD IDord-d02c5ab0d211469286bde2e8a6858570
Source noteuspto-grants-2015_07