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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1528828Generated: November 2, 2026

2-Fluoro-N-methylbenzylamine → 1-[4'-(4-{[(2-Fluoro-benzyl)-methyl-carbamoyl]-methyl}-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester

https://huagongshe.com/reaction/1528828

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-N-methylbenzylamineHCID 2060842—
Reactant1-[4'-(4-Carboxymethyl-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl esterHCID 66577387—
Product1-[4'-(4-{[(2-Fluoro-benzyl)-methyl-carbamoyl]-methyl}-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl esterHCID 66578122—

Reaction Steps

Prepared according to the procedure described in Example 33, Step 4, using 1-[4′-(4-carboxymethyl-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester and (2-fluoro-benzyl)-methyl-amine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09090573B2
Source datasetuspto-grants-2015_07
ORD IDord-be60bb276c8d4205ad95f495dc4d4cbe
Source noteuspto-grants-2015_07