Acetaldehyde → HCID 66578286, compound

HRID 1528842Notes

Reaction equation

HRID 1528842 reaction equation
[CH2:1]([O:3][C:4]([C:6]1([C:9]2[CH:14]=[CH:13][C:12]([C:15]3[CH:20]=[CH:19][C:18]([C:21]4[O:25][N:24]=[C:23]([CH3:26])[C:22]=4[CH2:27][NH:28][CH2:29][C@@H:30]([C:32]4[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=4)[CH3:31])=[CH:17][CH:16]=3)=[CH:11][CH:10]=2)[CH2:8][CH2:7]1)=[O:5])[CH3:2].[CH:38](=O)[CH3:39]>>[CH2:1]([O:3][C:4]([C:6]1([C:9]2[CH:10]=[CH:11][C:12]([C:15]3[CH:20]=[CH:19][C:18]([C:21]4[O:25][N:24]=[C:23]([CH3:26])[C:22]=4[CH2:27][N:28]([CH2:38][CH3:39])[CH2:29][C@@H:30]([C:32]4[CH:33]=[CH:34][CH:35]=[CH:36][CH:37]=4)[CH3:31])=[CH:17][CH:16]=3)=[CH:13][CH:14]=2)[CH2:7][CH2:8]1)=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 177AcetaldehydeHCID 66577468HCID 66577468, compound

Product 1

HCID 66578286HCID 66578286, compound

Procedure

Prepared according to the procedure described in Example 67, Step 1, using 1-(4′-{3-methyl-4-[((R)-2-phenyl-propylamino)-methyl]-isoxazol-5-yl}-biphenyl-4-yl)-cyclopropanecarboxylic acid ethyl ester and acetaldehyde.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-0ea69a489bcb4dce963b1036eec9058f
Source dataset
uspto-grants-2015_07
Patent number
US09090573B2

Reaction notes

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