2-Phenylethanethiol → 5-(4-Bromo-phenyl)-3-methyl-4-phenethylsulfanylmethyl-isoxazole

HRID 1528846Notes

Reaction equation

Br[CH2:2][C:3]1[C:4]([CH3:15])=[N:5][O:6][C:7]=1[C:8]1[CH:13]=[CH:12][C:11]([Br:14])=[CH:10][CH:9]=1.[C:16]1([CH2:22][CH2:23][SH:24])[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[Br:14][C:11]1[CH:12]=[CH:13][C:8]([C:7]2[O:6][N:5]=[C:4]([CH3:15])[C:3]=2[CH2:2][S:24][CH2:23][CH2:22][C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)=[CH:9][CH:10]=1

Participants

Reactant 2

HCID 781262-Phenylethanethiol

HCID 665772234-Bromomethyl-5-(4-bromo-phenyl)-3-methyl-isoxazole

Product 1

HCID 665784465-(4-Bromo-phenyl)-3-methyl-4-phenethylsulfanylmethyl-isoxazole

Procedure

Prepared according to the procedure described in Example 51, Step 1, using 4-bromomethyl-5-(4-bromo-phenyl)-3-methyl-isoxazole and 2-phenylethanethiol.

Workup

customPrepared

Sources & evidence

ORD record: ord-28f72d96195d478aaebf3a7871113285
Source dataset: uspto-grants-2015_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09090573B2

Reaction notes

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