Methyl iodide → HCID 66577790, compound

HRID 1528859Notes

Reaction equation

HRID 1528859 reaction equation
[CH3:1][C:2]1[C:6]([CH2:7][CH2:8][C:9](=[O:20])[NH:10][C:11]([CH3:19])([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH3:12])=[C:5]([C:21]2[CH:26]=[CH:25][C:24]([C:27]3[CH:32]=[CH:31][C:30]([C:33]4([C:36]([OH:38])=[O:37])[CH2:35][CH2:34]4)=[CH:29][CH:28]=3)=[CH:23][CH:22]=2)[O:4][N:3]=1.I[CH3:40]>>[CH3:1][C:2]1[C:6]([CH2:7][CH2:8][C:9](=[O:20])[N:10]([CH3:40])[C:11]([CH3:19])([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH3:12])=[C:5]([C:21]2[CH:22]=[CH:23][C:24]([C:27]3[CH:32]=[CH:31][C:30]([C:33]4([C:36]([OH:38])=[O:37])[CH2:34][CH2:35]4)=[CH:29][CH:28]=3)=[CH:25][CH:26]=2)[O:4][N:3]=1

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 66581945HCID 66581945, compound

Product 1

HCID 66577790HCID 66577790, compound

Procedure

Prepared according to the procedure described in Example 34, Step 4, using 1-(4′-{3-methyl-4-[2-(1-methyl-1-phenyl-ethylcarbamoyl)-ethyl]-isoxazol-5-yl}-biphenyl-4-yl)-cyclopropanecarboxylic acid and iodomethane.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-e74b50dbc97743e39d844fd4f7d2ba0f
Source dataset
uspto-grants-2015_07
Patent number
US09090573B2

Reaction notes

Loading…