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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1528865Generated: November 3, 2026

2-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl]butyric Acid Ethyl Ester → 2-[4'-(3-Methyl-4-phenethylsulfanylmethyl-isoxazol-5-yl)-biphenyl-4-yl]-butyric acid ethyl ester

https://huagongshe.com/reaction/1528865

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl]butyric Acid Ethyl EsterHCID 58539412—
Reactant5-(4-Bromo-phenyl)-3-methyl-4-phenethylsulfanylmethyl-isoxazoleHCID 66578446—
Product2-[4'-(3-Methyl-4-phenethylsulfanylmethyl-isoxazol-5-yl)-biphenyl-4-yl]-butyric acid ethyl esterHCID 66578560—

Reaction Steps

Prepared according to the procedure described in Example 108, Step 2, using 5-(4-bromo-phenyl)-3-methyl-4-phenethylsulfanylmethyl-isoxazole and 2-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-butyric acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09090573B2
Source datasetuspto-grants-2015_07
ORD IDord-6f351ad6e0a746d989f33a1b3779e4c3
Source noteuspto-grants-2015_07