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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1528882Generated: November 3, 2026

Methyl alpha,alpha-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzeneacetate → 2-Methyl-2-[4'-(3-methyl-4-phenethylsulfanylmethyl-isoxazol-5-yl)-biphenyl-4-yl]-propionic acid methyl ester

https://huagongshe.com/reaction/1528882

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl alpha,alpha-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzeneacetateHCID 57871083—
Reactant5-(4-Bromo-phenyl)-3-methyl-4-phenethylsulfanylmethyl-isoxazoleHCID 66578446—
Product2-Methyl-2-[4'-(3-methyl-4-phenethylsulfanylmethyl-isoxazol-5-yl)-biphenyl-4-yl]-propionic acid methyl esterHCID 66578663—

Reaction Steps

Prepared according to the procedure described in Example 3, Step 5, using 5-(4-bromo-phenyl)-3-methyl-4-phenethylsulfanylmethyl-isoxazole and 2-methyl-2-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-propionic acid methyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09090573B2
Source datasetuspto-grants-2015_07
ORD IDord-ecfee974cd6946118109411c9430c7ea
Source noteuspto-grants-2015_07