5-(4-Bromo-phenyl)-3-methyl-4-phenethylsulfanylmethyl-isoxazole → HCID 66578186, compound

HRID 1528887Notes

Reaction equation

HRID 1528887 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:12][N:11]=[C:10]([CH3:13])[C:9]=2[CH2:14][S:15][CH2:16][CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[CH:4][CH:3]=1.[CH2:24]([O:26][C:27](=[O:47])[CH:28]([C:32]1[CH:37]=[CH:36][C:35](B2OC(C)(C)C(C)(C)O2)=[CH:34][CH:33]=1)[CH:29]([CH3:31])[CH3:30])[CH3:25]>>[CH2:24]([O:26][C:27](=[O:47])[CH:28]([C:32]1[CH:33]=[CH:34][C:35]([C:2]2[CH:7]=[CH:6][C:5]([C:8]3[O:12][N:11]=[C:10]([CH3:13])[C:9]=3[CH2:14][S:15][CH2:16][CH2:17][C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)=[CH:4][CH:3]=2)=[CH:36][CH:37]=1)[CH:29]([CH3:31])[CH3:30])[CH3:25]

Participants

3

Reactant 2

HCID 665784465-(4-Bromo-phenyl)-3-methyl-4-phenethylsulfanylmethyl-isoxazoleHCID 66579921HCID 66579921, compound

Product 1

HCID 66578186HCID 66578186, compound

Procedure

Prepared according to the procedure described in Example 1, Step 7, using 5-(4-bromo-phenyl)-3-methyl-4-phenethylsulfanylmethyl-isoxazole and 3-methyl-2-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-butyric acid ethyl ester.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-4ff4cfdfb26a46c5a6e064698918c2fb
Source dataset
uspto-grants-2015_07
Patent number
US09090573B2

Reaction notes

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