Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1528889Generated: November 1, 2026

Methanesulfonyl chloride → 1-(4'-{4-[3-(Benzyl-methanesulfonyl-amino)-2-hydroxy-propyl]-3-methyl-isoxazol-5-yl}-biphenyl-4-yl)-cyclopropanecarboxylic acid ethyl ester

https://huagongshe.com/reaction/1528889

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanesulfonyl chlorideHCID 31297—
Reactant1-{4'-[4-(3-Benzylamino-2-hydroxy-propyl)-3-methyl-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl esterHCID 66577333—
Product1-(4'-{4-[3-(Benzyl-methanesulfonyl-amino)-2-hydroxy-propyl]-3-methyl-isoxazol-5-yl}-biphenyl-4-yl)-cyclopropanecarboxylic acid ethyl esterHCID 66578226—

Reaction Steps

Prepared according to the procedure described in Example 3, Step 7, using 1-{4′-[4-(3-benzylamino-2-hydroxy-propyl)-3-methyl-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl ester and methanesulfonyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09090573B2
Source datasetuspto-grants-2015_07
ORD IDord-eb38f19cf52641de9e5b0876a4d075c3
Source noteuspto-grants-2015_07