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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1528892Generated: November 1, 2026

Methanesulfonyl chloride → 1-(4'-{4-[2-(Benzyl-methanesulfonyl-amino)-ethyl]-3-methyl-isoxazol-5-yl}-biphenyl-4-yl)-cyclopropanecarboxylic acid ethyl ester

https://huagongshe.com/reaction/1528892

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanesulfonyl chlorideHCID 31297—
Reactant1-{4'-[4-(2-Benzylamino-ethyl)-3-methyl-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl esterHCID 66577241—
Product1-(4'-{4-[2-(Benzyl-methanesulfonyl-amino)-ethyl]-3-methyl-isoxazol-5-yl}-biphenyl-4-yl)-cyclopropanecarboxylic acid ethyl esterHCID 66578406—

Reaction Steps

Prepared according to the procedure described in Example 3, Step 7, using 1-{4′-[4-(2-benzylamino-ethyl)-3-methyl-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl ester and methane sulfonyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09090573B2
Source datasetuspto-grants-2015_07
ORD IDord-69762bf1ed404a308075e4c0b079f596
Source noteuspto-grants-2015_07