5-(4-Bromo-phenyl)-3-methyl-isoxazole-4-carbaldehyde → 1-[5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-yl]prop-2-en-1-ol

HRID 1528910Notes

Reaction equation

HRID 1528910 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:12][N:11]=[C:10]([CH3:13])[C:9]=2[CH:14]=[O:15])=[CH:4][CH:3]=1.[CH:16]([Mg]Br)=[CH2:17]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[O:12][N:11]=[C:10]([CH3:13])[C:9]=2[CH:14]([OH:15])[CH:16]=[CH2:17])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 821337925-(4-Bromo-phenyl)-3-methyl-isoxazole-4-carbaldehydeHCID 178418507HCID 178418507, compound

Product 1

HCID 665821121-[5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-yl]prop-2-en-1-ol

Procedure

Prepared according to the procedure described in Example 114, Step 3, using 5-(4-bromo-phenyl)-3-methyl-isoxazole-4-carbaldehyde and vinylmagnesium bromide.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-c324021bc0574e5690110bd5490394af
Source dataset
uspto-grants-2015_07
Patent number
US09090573B2

Reaction notes

Loading…