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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1528936Generated: November 4, 2026

Iodobenzene → 1-{4'-[4-((E)-1-Hydroxy-2,2-dimethyl-4-phenyl-but-3-enyl)-3-methyl-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl ester

https://huagongshe.com/reaction/1528936

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIodobenzeneHCID 11575—
Reactant1-{4'-[4-(1-Hydroxy-2,2-dimethyl-but-3-enyl)-3-methyl-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl esterHCID 66577390—
Product1-{4'-[4-((E)-1-Hydroxy-2,2-dimethyl-4-phenyl-but-3-enyl)-3-methyl-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl esterHCID 66577392—

Reaction Steps

Prepared according to the procedure described in Example 168, Step 1, using 1-{4′-[4-(1-hydroxy-2,2-dimethyl-but-3-enyl)-3-methyl-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl ester and iodobenzene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09090573B2
Source datasetuspto-grants-2015_07
ORD IDord-5bd865eab2e2466c81bceaba0b5cac34
Source noteuspto-grants-2015_07