Benzylamine → 2-Benzylamino-2-[5-(4-bromo-phenyl)-3-methyl-isoxazol-4-yl]-ethanol

HRID 1528949Notes

Reaction equation

HRID 1528949 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:12][N:11]=[C:10]([CH3:13])[C:9]=2[CH:14]2[CH2:16][O:15]2)=[CH:4][CH:3]=1.[CH2:17]([NH2:24])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[CH2:17]([NH:24][CH:14]([C:9]1[C:10]([CH3:13])=[N:11][O:12][C:8]=1[C:5]1[CH:6]=[CH:7][C:2]([Br:1])=[CH:3][CH:4]=1)[CH2:16][OH:15])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

Participants

3

Reactant 2

HCID 7504BenzylamineHCID 866524045-(4-Bromo-phenyl)-3-methyl-4-oxiranyl-isoxazole

Product 1

HCID 665783882-Benzylamino-2-[5-(4-bromo-phenyl)-3-methyl-isoxazol-4-yl]-ethanol

Procedure

Prepared according to the procedure described in Example 187, Step 2, using 5-(4-bromo-phenyl)-3-methyl-4-oxiranyl-isoxazole and benzyl amine.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-56aefd707d3e45a2a102b3510650e580
Source dataset
uspto-grants-2015_07
Patent number
US09090573B2

Reaction notes

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