4-Methylpyrazole → HCID 66578104, compound

HRID 1528955Notes

Reaction equation

HRID 1528955 reaction equation
C([O:3][C:4]([C:6]1([C:9]2[CH:14]=[CH:13][C:12]([C:15]3[CH:20]=[CH:19][C:18]([C:21]4[O:25][N:24]=[C:23]([CH3:26])[C:22]=4[CH2:27]Br)=[CH:17][CH:16]=3)=[CH:11][CH:10]=2)[CH2:8][CH2:7]1)=[O:5])C.[CH3:29][C:30]1[CH:31]=[N:32][NH:33][CH:34]=1>>[CH3:26][C:23]1[C:22]([CH2:27][N:32]2[CH:31]=[C:30]([CH3:29])[CH:34]=[N:33]2)=[C:21]([C:18]2[CH:17]=[CH:16][C:15]([C:12]3[CH:11]=[CH:10][C:9]([C:6]4([C:4]([OH:3])=[O:5])[CH2:7][CH2:8]4)=[CH:14][CH:13]=3)=[CH:20][CH:19]=2)[O:25][N:24]=1

Participants

3

Reactant 2

HCID 34064-MethylpyrazoleHCID 665771991-[4'-(4-Bromomethyl-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester

Product 1

HCID 66578104HCID 66578104, compound

Procedure

Prepared according to the procedure described in Example 34, Step 4, using 1-[4′-(4-bromomethyl-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester and 4-methyl-1H-pyrazole.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-7272ce7a95a44482810834e06456fd22
Source dataset
uspto-grants-2015_07
Patent number
US09090573B2

Reaction notes

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