HCID 53405104, compound → HCID 66578859, compound

HRID 1528965Notes

Reaction equation

HRID 1528965 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:12][N:11]=[C:10]([CH3:13])[C:9]=2[CH:14]([OH:24])[CH2:15][CH2:16][CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[CH:4][CH:3]=1.[CH3:25][O:26][C:27](=[O:45])[CH2:28][CH2:29][C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][C:31]=1B1OC(C)(C)C(C)(C)O1>>[CH3:25][O:26][C:27](=[O:45])[CH2:28][CH2:29][C:30]1[CH:31]=[CH:32][CH:33]=[CH:34][C:35]=1[C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:12][N:11]=[C:10]([CH3:13])[C:9]=2[CH:14]([OH:24])[CH2:15][CH2:16][CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 53405104HCID 53405104, compoundHCID 665784451-[5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-yl]-4-phenyl-butan-1-ol

Product 1

HCID 66578859HCID 66578859, compound

Procedure

Prepared according to the procedure described in Example 110, Step 3, using 1-[5-(4-bromo-phenyl)-3-methyl-isoxazol-4-yl]-4-phenyl-butan-1-ol and 3-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-propionic acid methyl ester.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-14ea2ae003be455bbad812b316575506
Source dataset
uspto-grants-2015_07
Patent number
US09090573B2

Reaction notes

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