Ethyl 2-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)phenyl)acetate → (4'-{4-[2-(4-Methoxy-phenyl)-1-methyl-ethylamino]-3-methyl-isoxazol-5-yl}-biphenyl-2-yl)-acetic acid ethyl ester

Participants

Role	Name	HCID	Charge
Reactant	Ethyl 2-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)phenyl)acetate	HCID 58539376	—
Reactant	[5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-yl]-[2-(4-methoxy-phenyl)-1-methyl-ethyl]-amine	HCID 66578348	—
Product	(4'-{4-[2-(4-Methoxy-phenyl)-1-methyl-ethylamino]-3-methyl-isoxazol-5-yl}-biphenyl-2-yl)-acetic acid ethyl ester	HCID 66582147	—

Reaction Steps

Prepared according to the procedure described in Example 1, Step 7, using [5-(4-bromo-phenyl)-3-methyl-isoxazol-4-yl]-[2-(4-methoxy-phenyl)-1-methyl-ethyl]-amine and [2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]acetic acid ethyl ester.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US09090573B2
Source dataset	uspto-grants-2015_07
ORD ID	ord-ccf0b22a1bf24ddbb8202bba03956af4
Source note	uspto-grants-2015_07