HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 1-[(4-Bromophenyl)methyl]cyclopropanecarboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 66578489 | HCID 66578489 | — |
| Product | 1-[(4-Bromophenyl)methyl]cyclopropanecarboxylic acid | HCID 65811456 | — |
Reaction Steps
1-(4-Bromo-benzyl)-cyclopropanecarbonitrile (from the previous step) was dissolved in MeOH and NaOH (35% aq.) and the reaction was heated to reflux for 8 hours. After cooling the reaction was submitted to standard acid-base workup to afford the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09090573B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-d6fa3e0e3dc248e0966074ae4b52bb24 |
| Source note | uspto-grants-2015_07 |