HCID 87057700, compound → HCID 66578673, compound

HRID 1529045Notes

Reaction equation

HRID 1529045 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:12][N:11]=[C:10]([CH3:13])[C:9]=2/[CH:14]=[N:15]/[S:16]([CH3:19])(=[O:18])=[O:17])=[CH:4][CH:3]=1.[C:20]1([CH2:26][CH2:27][CH2:28][Mg]Br)[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:12][N:11]=[C:10]([CH3:13])[C:9]=2[CH:14]([NH:15][S:16]([CH3:19])(=[O:18])=[O:17])[CH2:28][CH2:27][CH2:26][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 87057700HCID 87057700, compoundHCID 178418471HCID 178418471, compound

Product 1

HCID 66578673HCID 66578673, compound

Procedure

Prepared according to the procedure described in Example 114, Step 3, using N-[1-[5-(4-bromo-phenyl)-3-methyl-isoxazol-4-yl]-meth-(E)-ylidene]-methanesulfonamide and 3-(phenyl)propylmagnesium bromide.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-80c7fe5b4d824b9eb047a761b9658329
Source dataset
uspto-grants-2015_07
Patent number
US09090573B2

Reaction notes

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