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HRID 1529060作成日：2026年10月27日

Ethyl (4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetate → (4'-{4-[1-Hydroxy-2-(3-trifluoromethyl-benzylsulfanyl)-ethyl]-3-methyl-isoxazol-5-yl}-biphenyl-4-yl)-acetic acid ethyl ester

https://huagongshe.com/reaction/1529060

反応式

関与物質

役割名称HCID仕込み量
反応物Ethyl (4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetateHCID 46737998—
反応物1-[5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-yl]-2-(3-trifluoromethyl-benzylsulfanyl)-ethanolHCID 66577288—
生成物(4'-{4-[1-Hydroxy-2-(3-trifluoromethyl-benzylsulfanyl)-ethyl]-3-methyl-isoxazol-5-yl}-biphenyl-4-yl)-acetic acid ethyl esterHCID 66578460—

反応手順

Prepared according to the procedure described in Example 1, Step 7, using 1-[5-(4-bromo-phenyl)-3-methyl-isoxazol-4-yl]-2-(3-trifluoromethyl-benzylsulfanyl)-ethanol and [4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-acetic acid ethyl ester.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US09090573B2
出典データセットuspto-grants-2015_07
ORD IDord-9da34f4816304286b781c37207596188
出典メモuspto-grants-2015_07