4-(2-Ethoxycarbonylethyl)benzeneboronic acid → HCID 66578939, compound

HRID 1529070Notes

Reaction equation

HRID 1529070 reaction equation
[CH2:1]([S:8][CH2:9][C@H:10]([C:12]1[C:13]([CH3:24])=[N:14][O:15][C:16]=1[C:17]1[CH:22]=[CH:21][C:20](Br)=[CH:19][CH:18]=1)[OH:11])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:25]([O:27][C:28]([CH2:30][CH2:31][C:32]1[CH:37]=[CH:36][C:35](B(O)O)=[CH:34][CH:33]=1)=[O:29])[CH3:26]>>[CH2:25]([O:27][C:28](=[O:29])[CH2:30][CH2:31][C:32]1[CH:37]=[CH:36][C:35]([C:20]2[CH:21]=[CH:22][C:17]([C:16]3[O:15][N:14]=[C:13]([CH3:24])[C:12]=3[C@H:10]([OH:11])[CH2:9][S:8][CH2:1][C:2]3[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=3)=[CH:18][CH:19]=2)=[CH:34][CH:33]=1)[CH3:26]

Participants

3

Reactant 2

HCID 38517004-(2-Ethoxycarbonylethyl)benzeneboronic acidHCID 66577407HCID 66577407, compound

Product 1

HCID 66578939HCID 66578939, compound

Procedure

Prepared according to the procedure described in Example 1, Step 7, using (S)-2-benzylsulfanyl-1-[5-(4-bromo-phenyl)-3-methyl-isoxazol-4-yl]-ethanol and [4-(2-ethoxycarbonylethyl)phenyl]boronic acid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-2c102d0b1fc440a2b8a6591ee9bd6e31
Source dataset
uspto-grants-2015_07
Patent number
US09090573B2

Reaction notes

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