3-(Trifluoromethyl)benzyl mercaptan → 1-[5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-yl]-2-(3-trifluoromethyl-benzylsulfanyl)-ethanone

HRID 1529071Notes

Reaction equation

HRID 1529071 reaction equation
Br[CH2:2][C:3]([C:5]1[C:6]([CH3:17])=[N:7][O:8][C:9]=1[C:10]1[CH:15]=[CH:14][C:13]([Br:16])=[CH:12][CH:11]=1)=[O:4].[F:18][C:19]([F:29])([F:28])[C:20]1[CH:21]=[C:22]([CH2:26][SH:27])[CH:23]=[CH:24][CH:25]=1>>[Br:16][C:13]1[CH:14]=[CH:15][C:10]([C:9]2[O:8][N:7]=[C:6]([CH3:17])[C:5]=2[C:3](=[O:4])[CH2:2][S:27][CH2:26][C:22]2[CH:23]=[CH:24][CH:25]=[C:20]([C:19]([F:18])([F:28])[F:29])[CH:21]=2)=[CH:11][CH:12]=1

Participants

3

Reactant 2

HCID 1412363-(Trifluoromethyl)benzyl mercaptanHCID 86652406HCID 86652406, compound

Product 1

HCID 665773411-[5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-yl]-2-(3-trifluoromethyl-benzylsulfanyl)-ethanone

Procedure

Prepared according to the procedure described in Example 3, Step 7, using 2-bromo-1-[5-(4-bromo-phenyl)-3-methyl-isoxazol-4-yl]-ethanone and (3-trifluoromethyl-phenyl)-methanethiol.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-ea266b0b522645da8b0baeb9ac174107
Source dataset
uspto-grants-2015_07
Patent number
US09090573B2

Reaction notes

Loading…