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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1529102Generated: November 3, 2026

2-Bromo-6-propoxypyridine → 1-{4'-[3-Methyl-4-(6-propoxy-pyridin-2-ylamino)-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl ester

https://huagongshe.com/reaction/1529102

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-6-propoxypyridineHCID 23557398—
Reactant1-[4'-(4-Amino-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl esterHCID 66577195—
Product1-{4'-[3-Methyl-4-(6-propoxy-pyridin-2-ylamino)-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl esterHCID 66578457—

Reaction Steps

Prepared according to the procedure described in Example 290, Step 1, using 1-[4′-(4-amino-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester and 2-bromo-6-propoxy-pyridine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09090573B2
Source datasetuspto-grants-2015_07
ORD IDord-5c4b5ac914174d9cb7f28c79cdc50cf2
Source noteuspto-grants-2015_07