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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1529103Generated: November 4, 2026

2-Bromo-6-ethoxypyridine → 1-{4'-[4-(6-Ethoxy-pyridin-2-ylamino)-3-methyl-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl ester

https://huagongshe.com/reaction/1529103

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-6-ethoxypyridineHCID 1201018—
Reactant1-[4'-(4-Amino-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl esterHCID 66577195—
Product1-{4'-[4-(6-Ethoxy-pyridin-2-ylamino)-3-methyl-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl esterHCID 66578495—

Reaction Steps

Prepared according to the procedure described in Example 290, Step 1, using 1-[4′-(4-amino-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester and 2-bromo-6-ethoxy-pyridine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09090573B2
Source datasetuspto-grants-2015_07
ORD IDord-5ff96996654e454d90026888be44e9b6
Source noteuspto-grants-2015_07