6-Bromo-N-[2-(dimethylamino)ethyl]-2-pyridinecarboxamide → HCID 66578365, compound

HRID 1529110Notes

Reaction equation

HRID 1529110 reaction equation
[CH2:1]([O:3][C:4]([C:6]1([C:9]2[CH:14]=[CH:13][C:12]([C:15]3[CH:20]=[CH:19][C:18]([C:21]4[O:25][N:24]=[C:23]([CH3:26])[C:22]=4[NH2:27])=[CH:17][CH:16]=3)=[CH:11][CH:10]=2)[CH2:8][CH2:7]1)=[O:5])[CH3:2].[CH3:28][N:29]([CH3:42])[CH2:30][CH2:31][NH:32][C:33]([C:35]1[CH:40]=[CH:39][CH:38]=[C:37](Br)[N:36]=1)=[O:34]>>[CH2:1]([O:3][C:4]([C:6]1([C:9]2[CH:10]=[CH:11][C:12]([C:15]3[CH:20]=[CH:19][C:18]([C:21]4[O:25][N:24]=[C:23]([CH3:26])[C:22]=4[NH:27][C:37]4[CH:38]=[CH:39][CH:40]=[C:35]([C:33](=[O:34])[NH:32][CH2:31][CH2:30][N:29]([CH3:28])[CH3:42])[N:36]=4)=[CH:17][CH:16]=3)=[CH:13][CH:14]=2)[CH2:8][CH2:7]1)=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 592770906-Bromo-N-[2-(dimethylamino)ethyl]-2-pyridinecarboxamideHCID 665771951-[4'-(4-Amino-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester

Product 1

HCID 66578365HCID 66578365, compound

Procedure

Prepared according to the procedure described in Example 290, Step 1, using 1-[4′-(4-amino-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester and 6-bromo-pyridine-2-carboxylic acid (2-dimethylamino-ethyl)-amide.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-b3adb20ec86d424ba3d9ec9584ddb92c
Source dataset
uspto-grants-2015_07
Patent number
US09090573B2

Reaction notes

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