3-Carboxyphenylboronic acid → HCID 66578708, compound

HRID 1529118Notes

Reaction equation

HRID 1529118 reaction equation
[CH2:1]([O:8][C:9](=[O:25])[NH:10][CH2:11][C:12]1[C:13]([CH3:24])=[N:14][O:15][C:16]=1[C:17]1[CH:22]=[CH:21][C:20](Br)=[CH:19][CH:18]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:26]([C:29]1[CH:30]=[C:31](B(O)O)[CH:32]=[CH:33][CH:34]=1)([OH:28])=[O:27]>>[CH2:1]([O:8][C:9]([NH:10][CH2:11][C:12]1[C:13]([CH3:24])=[N:14][O:15][C:16]=1[C:17]1[CH:22]=[CH:21][C:20]([C:33]2[CH:32]=[CH:31][CH:30]=[C:29]([C:26]([OH:28])=[O:27])[CH:34]=2)=[CH:19][CH:18]=1)=[O:25])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 27339573-Carboxyphenylboronic acidHCID 66578238HCID 66578238, compound

Product 1

HCID 66578708HCID 66578708, compound

Procedure

Prepared according to the procedure described in Example 108, Step 2, using [5-(4-bromo-phenyl)-3-methyl-isoxazol-4-ylmethyl]-carbamic acid benzyl ester and 3-carboxyphenylboronic acid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-88eed87a37a94af0b2bbf0aa6b4532d1
Source dataset
uspto-grants-2015_07
Patent number
US09090573B2

Reaction notes

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