Iodobenzene → HCID 66582181, compound

HRID 1529138Notes

Reaction equation

HRID 1529138 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:12][N:11]=[C:10]([CH3:13])[C:9]=2[CH:14]([OH:20])[C:15]([F:19])([F:18])[CH:16]=[CH2:17])=[CH:4][CH:3]=1.I[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[O:12][N:11]=[C:10]([CH3:13])[C:9]=2[CH:14]([OH:20])[C:15]([F:18])([F:19])/[CH:16]=[CH:17]/[C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 11575IodobenzeneHCID 66577474HCID 66577474, compound

Product 1

HCID 66582181HCID 66582181, compound

Procedure

Prepared according to the procedure described in Example 124, Step 1, using 1-[5-(4-bromo-phenyl)-3-methyl-isoxazol-4-yl]-2,2-difluoro-but-3-en-1-ol and iodobenzene.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-e58389cf2d5b4330988b736d58461732
Source dataset
uspto-grants-2015_07
Patent number
US09090573B2

Reaction notes

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