HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodine → 5-(2-chloro-6-fluorophenyl)-3-iodo-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodine | HCID 807 | — |
| Reactant | 5-(2-chloro-6-fluorophenyl)-1H-indole | HCID 67959577 | — |
| Product | 5-(2-chloro-6-fluorophenyl)-3-iodo-1H-indole | HCID 67960105 | 103.2% |
Reaction Steps
This title compound was prepared analogously to compound 25c using 5-(2-chloro-6-fluorophenyl)-1H-indole (15 g, 0.06 mol) and I2 (17.1 g, 0.15 mol) to obtain the crude title compound (23 g). MS (ESI, m/z): 370.8 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09090593B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-d1c0eff3fe194b41a7477b98b1cb9fcd |
| Source note | uspto-grants-2015_07 |