反应详情

0.450 g (S)-5-dibenzylamino-1-methylpiperidin-2-one are suspended in 25 ml of methanol and hydrogenated with 0.150 g Pd/C 10% at a pressure of 3 bar and a temperature of 60° C. After 16 hours the catalyst is removed by suction filtering and the filtrate is evaporated to dryness. 0.190g of the product are obtained as an oil.

1. customa temperature of 60° C
2. customAfter 16 hours the catalyst is removed by suction
3. filtrationfiltering
4. customthe filtrate is evaporated to dryness