HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Bromide → 3-ethyl-1H-indol-6-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Bromide | HCID 6332 | — |
| Reactant | 6-Nitro-1H-indole | HCID 78502 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 3-ethyl-1H-indol-6-amine | HCID 45117014 | — |
Reaction Steps
3-Ethyl-1H-indol-6-ylamine (B-12) was synthesized following the general scheme above starting from 6-nitroindole and ethyl bromide. Overall yield (42%). HPLC ret. time 1.95 min, 10-99% CH3CN, 5 min run; ESI-MS 161.3 m/z (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09090619B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-3dee4391ee1249938e01c3bedfabb45c |
| Source note | uspto-grants-2015_07 |