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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1529636Generated: October 26, 2026

Ethyl iodoacetate → (6-Amino-1H-indol-3-yl)-acetic acid ethyl ester

https://huagongshe.com/reaction/1529636

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl iodoacetateHCID 12183—
Reactant6-Nitro-1H-indoleHCID 78502—
Product(6-Amino-1H-indol-3-yl)-acetic acid ethyl esterHCID 66675483—

Reaction Steps

(6-Amino-1H-indol-3-yl)-acetic acid ethyl ester (B-17) was synthesized following the general scheme above starting from 6-nitroindole and iodo-acetic acid ethyl ester. Overall yield (24%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09090619B2
Source datasetuspto-grants-2015_07
ORD IDord-dd8632bca5ca4433b8dab4ee4df44a52
Source noteuspto-grants-2015_07