Nicotinic Acid → HCID 86673654, compound

Participants

Reaction Conditions

Reaction Steps

Nicotinic acid (75 g, 0.61 mmoles) and 10 mL of xylene were charged to a reactor that is equipped with a sub-surface nitrogen flow, a Dean-Stark trap filled with 25 mL of xylene, and a mechanical stirrer. Oleylamine (163.2 g, 0.61 moles) was added to this mixture dropwise. The mixture was heated to up to 200° C. and held until about 6 mL of water collected in the Dean-Stark trap. The temperature was reduced to about 120° C. and the mixture was then vacuum stripped to provide a dark residue that had a TBN of 168.6 by D2896 method and had infra-red bands at 3300.7, 1626.4, 1545.5, and 707.6 cm−1.

Provenance & Evidence