Benzoyl chloride → Cyclohexanecarbonyl chloride

HRID 1530754Notes

Reaction equation

HRID 1530754 reaction equation
[C:1]([Cl:9])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C[Mg]Cl>>[CH2:4]1[CH2:5][CH2:6][CH2:7][CH:2]([C:1]([Cl:9])=[O:8])[CH2:3]1

Participants

3

Reactant 2

HCID 7412Benzoyl chlorideHCID 178418332HCID 178418332, compound

Product 1

HCID 75938Cyclohexanecarbonyl chloride

Procedure

Compound of formula (XI) where all R5s are H and R7 and R8 are methyl was prepared by reacting 4-PgO benzoic acid chloride, prepared as in the above paragraph, in a Grignard reaction with CH3MgCl in a procedure similar that employed in Example I for producing (1-methyl-l-hydroxy) ethyl-3-cyclohexene from 3-cyclohexane carboxylic acid chloride.

Workup

  1. customR8 are methyl was prepared

Sources & evidence

ORD record
ord-f9db31b1eab54f7b961fcb5a525c682d
Source dataset
uspto-grants-2001_03
Patent number
US06197122B1

Reaction notes

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