HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromomethyl methyl ether → HCID 21252632, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromomethyl methyl ether | HCID 83093 | — |
| Reactant | HCID 70118057 | HCID 70118057 | — |
| Catalyst | Benzyltriethylammonium bromide | HCID 165294 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 21252632 | HCID 21252632 | — |
Reaction Steps
The 2-(vinyltrityl)phenol (1.0 equiv.) is dissolved in CH2Cl2/50% KOH/H2O. Benzyltriethyl ammonium bromide is added as a phase transfer agent (0.1 equiv.). To this two phase mixture is added bromomethylmethylether (MOMBr). The reaction is allowed to stir for 30 minutes. The organic phase is separated, washed with water and brine before being dried with MgSO4. Solvent is removed to yield the MOM-protected 2-triphenylmethylphenol in near quantitative yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06197715B1 |
| Source dataset | uspto-grants-2001_03 |
| ORD ID | ord-6f81d81d9af444e6b186cdf6706f1947 |
| Source note | uspto-grants-2001_03 |