化工社化工社 化学情報印刷レポート · 研究参考用
Dimethyl (4-hydroxyphenyl)malonate → Dimethyl (4-hydroxycyclohexyl)malonate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dimethyl (4-hydroxyphenyl)malonate | HCID 3018973 | — |
| 反応物 | HCID 178418361 | HCID 178418361 | — |
| 触媒 | Rhodium | HCID 23948 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | Dimethyl (4-hydroxycyclohexyl)malonate | HCID 91368111 | — |
反応手順
At 60° C. and a hydrogen pressure of 150 bar, 67.3 g of dimethyl (4-hydroxyphenyl)malonate in 500 ml of methanol were hydrogenated in the presence of 5 g of rhodium/carbon catalyst (5%). The catalyst was filtered off and the mixture was concentrated. This to give the title product as a colourless oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06197729B1 |
| 出典データセット | uspto-grants-2001_03 |
| ORD ID | ord-680e2cf6c9d64e7d9dcd6c264458d4fe |
| 出典メモ | uspto-grants-2001_03 |