反应详情

At room temperature, 56.2 g (284 mmol) of 4-(1-hydroxy-2,2,2-trifluoroethyl)cyclohexanol and 91.7 g of pyridinium chlorochromate were stirred in 1 l of dichloromethane for 8 hours. The solvent was removed under reduced pressure and the residue was purified by filtration through silica gel (heptane/ethyl acetate 1:1), to give the title product as a colourless oil.

1. customThe solvent was removed under reduced pressure
2. filtrationthe residue was purified by filtration through silica gel (heptane/ethyl acetate 1:1)