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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1530840Generated: November 3, 2026

HCID 15524191, compound → 5-Bromo-1,2,3,4-tetrahydro-2-(2-phenylethyl)-7,8-isoquinolinediamine

https://huagongshe.com/reaction/1530840

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 15524191HCID 15524191—
CatalystNickelHCID 935—
SolventTetrahydrofuranHCID 8028—
Product5-Bromo-1,2,3,4-tetrahydro-2-(2-phenylethyl)-7,8-isoquinolinediamineHCID 1552419298%

Reaction Steps

A solution of the product from Example 9 (0.6 g, 1. mmol) in THF (50 mL) was stirred over RaNi under a hydrogen balloon for 40 mins. The catalyst was filtered off and concentrated under vacuum to give the title compound (0.54 g, 98% yield) as a pink solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06197771B1
Source datasetuspto-grants-2001_03
ORD IDord-c77ee639bd804723877eebb1906c2834
Source noteuspto-grants-2001_03